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There is no receptor that AOD9604 was optimized to bind, and this is not an oversight in the literature but a genuine feature of the compound's origin
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The iron-chelating potential of each ACM, but also their combination, which resembles iron chelation combination therapy, is likely to be involved in anticancer activity through the targeting of iron involved in free radical damage, in iron toxins involved in carcinogenicity, in iron proteins and associated metabolic pathways including ferroptosis associated with cancer, and other similar mechanisms