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Current research suggests it acts primarily through: Stimulation of angiogenesis — the formation of new blood vessels in damaged tissues Modulation of the NO (nitric oxide) system , involved in vasodilation and wound healing Interaction with the gut-brain axis , via the dopaminergic and serotonergic systems Regulation of growth factors , including VEGF, FGF, and EGF Gut Healing Benefits The most extensively studied area of BPC-157 research is arguably its effect on the gastrointestinal system