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Although the cryo-EM map was determined at medium resolution, we could build a reliable model by fitting the crystal structures of NK1 dimer as well as the SEMA, PSI, IPT1, and IPT2 domains of c-MET into a cryo-EM map with minor adjustment 24,30 (Supplementary Fig
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In contrast, recent reports indicate that AMAP is cytotoxic in primary human hepatocytes or precision-cut human liver slices [30,31]