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Furthermore, the oligomerization domain mutant Mid51 (R169W) has recently been identified as a potential candidate genetic variant for PD as it can inhibit inter-lysosomal untethering events mediated by MLCSs, resulting in the dysregulation of lysosomal network dynamics (Wong et al., 2022)

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Singh A., Kukreti R., Saso L., and Kukreti S., “Oxidative Stress: A Key Modulator in Neurodegenerative Diseases,” Molecules 24 (2019): 1583, 10.3390/molecules24081583